GI · CMS status A
45381
Colonoscopy submucous njx
Colonoscopy, flexible; with directed submucosal injection.
Published by RVUDoc. Numeric data: CMS RVU26C, effective 2026-07-01. Page updated 2026-09-23. Calculation limits and editorial policy.
Work RVU
3.47
National non-QP estimate
$490.33
National GPCI · non-facility · CF $33.4009
Fee-schedule estimate before claim adjustments. Coverage, setting and payer rules still apply.
RVU anatomyWork 3.47 + Practice 10.79 + Malpractice 0.42 = 14.68 total
Work (your effort)Practice expenseMalpractice
Billing guidance for 45381 is locked
- When to use it: the exact clinical situations that support billing 45381
- Documentation checklist: the 3 elements your note needs before submitting
- Common pitfalls: the 1 mistakes that get 45381 downcoded or denied
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Common modifiers
59
Common ICD-10 pairings
K63.5
Related codes
These include alternative services and possible add-ons. Listing codes together does not establish that they can be billed together; check the applicable edits and payer policy.
See what 45381 adds to your year
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Educational reference, not billing or legal advice. Verify against your payer contracts and your compliance team before submission.