GI · CMS status A
45380
Colonoscopy w/ biopsy
Colonoscopy, flexible; with biopsy, single or multiple.
Work RVU
3.91
2026 Medicare pays
$326.99
National GPCI · non-facility · CF $33.4009
RVU anatomyWork 3.91 + Practice 5.49 + Malpractice 0.39 = 9.79 total
Work (your effort)Practice expenseMalpractice
Billing guidance for 45380 is locked
- When to use it: the exact clinical situations that support billing 45380
- Documentation checklist: the 3 elements your note needs before submitting
- Common pitfalls: the 1 mistakes that get 45380 downcoded or denied
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Common modifiers
PT33
Common ICD-10 pairings
K63.5K51.90
Educational reference, not billing or legal advice. Verify against your payer contracts and your compliance team before submission.